곤충생리학
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Insect Molecular Physiology Laboratory

Pelple

  • Kim, Yonggyun - Professor
  • Surakasi Venkata Prasad - Postdoctoral associate
  • Kim, Jaehyun - MS candidate
  • Son, Yerim - MS candidate
  • Park, Bokri - MS candidate
  • Hwang, Jihyun - MS candidate
  • Seo, Samyeol - MS candidate
  • Kim, Jiwan - MS candidate
  • Park, Jung-Ah - MS candidate
  • Suk, Jungkyun - Undergraduate
  • Cho, Eunran - Undergraduate

곤충생리학

Research Interest

Our research interest focuses on insect development and immune systems. To understand these physiological processes, we use two models. Research direction of the first model system is to determine molecular interactions between Spodoptera exigua and Xenorhabdus nematophila. An entomopathogenic bacterium, X. nematophila, suppresses insect immune responses by inhibiting eicosanoid biosynthesis using PLA2 inhibitors. Currently we discover that prostaglandins mediate hemocyte behaviors in response to bacterial challenge using a G protein-coupled receptor, which is the first report in insect system. To develop novel insecticides, we chemically identified several bacterial metabolites from X. nematophila. These bacterial metabolites are patented.

곤충생리학

The other research direction is to understand molecular interactions between Plutella xylostella and Cotesia plutellae bracovirus (CpBV). We performed functional genomic study on CpBV, which contains more than 470 kb with a prediction of more than 100 genes. Various viral genes are implicated in altering insect development and immune processes.

곤충생리학

Current Publications

Kim B, Kim Y. 2010. Transient transcription of a putative RNase containing BEN domain encoded in Cotesia plutellae bracovirus induces an immunosuppression of the diamondback moth, Plutella xylostella. J. Invertebr. Pathol. 105: 156-163.
Kim J, Kim Y. 2010. A viral histone H4 suppresses expression of a transferrin that plays a role in the immune response of the diamondback moth, Plutella xylostella. Insect Mol. Biol. 19: 567-574.
Barandoc KP, Kim Y. 2010. Transient inhibitory factors encoded in Cotesia plutellae bracovirus require the 5'-UTR of a host mRNA target. Comp. Biochem. Physiol. B. 156: 129-136.
Kim GS, Kim Y. 2010. Up-regulation of circulating hemocyte population in response to bacterial challenge is mediated by octopamine and 5-hydroxytryptamine via Rac1 signal in Spodoptera exigua. J. Insect Physiol. 56: 559-566.
Barandoc KP, Kim J. Kim Y. 2010. Cotesia plutellae bracovirus suppresses expression of an antimicrobial peptide, cecropin, in the diamondback moth, Plutella xylostella, challenges by bacteria. J. Microbiol. 48: 117-123.
Shrestha S, Park Y, Stanley D, Kim Y. 2010. Genes encoding phospholipase A2 mediate insect nodulation reactions to bacterial challenge. J. Insect Physiol. 56: 324-332.
Shrestha S, Kim Y. 2010. Activation of immune-associated phospholipase A2 id functionally linked to Toll/Imd pathways in the red flour beetle, Tribolium castaneum. Dev. Comp. Immunol. 34: 530-537.

Position Available

Any excellent postdoctoral associate, PhD and MS candidates may apply to our research group. Please contact to Dr. Yonggyun Kim (hosanna@andong.ac.kr)